Prolonged endotracheal intubation is related to various complications including ventilator related pneumonia, airway harm, or threat of reintubation. Reintubation is a specific drawback particularly due to the inability to cooperate with peri-extubation maneuvers, and the comparatively excessive sedation necessities. Children who've excessive thirst may have high blood sugar ranges. In conclusion, several studies have advised that prophylactic NIV could reduce the chance of post-extubation respiratory failure in ICU patients at excessive danger of extubation failure. Further research are wanted to elucidate the efficacy of HFNC throughout weaning from prolonged mechanical ventilation in a bigger inhabitants to prevent put up-extubation respiratory failure in patients at high risk of extubation failure in the intensive care unit and such a clinical situation the place NIV shouldn't be really useful. 106 mm Hg), with the intention to avoid tracheostomy on ICU day sixteen the primary weaning attempt was made. We advocate that the first setting of HFNC stream be the identical as the maximum inspiratory flow of the ventilator throughout stress support ventilation, and day and night glucose routine the duration of HFNC be steadily prolonged together with physiotherapy rehabilitation. It is necessary, nonetheless, that you discuss this together with your private physician and first receive acceptable lab checks